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Filtered Search Results
Medchemexpress LLC CID 697851 | 312508-42-2 | C14H12N4OS | 5 MG
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CID 697851 is a solid, light yellow to yellow compound that functions as an AddAB and RecBCD inhibitor. It offers IC50s of 13 and 33 nM, making it suitable for antibacterial research.
- Functions as an AddAB and RecBCD inhibitor
- Offers IC50s of 13 and 33 nM
- Suitable for antibacterial research
- High purity (99.49%)
- Solid appearance
- Color ranges from light yellow to yellow
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Cayman Chemical ANTIBODY DImyrIstIn 250mg
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A diacylglycerol
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Cayman Chemical -MethylamIno-L-AlnInhydr 5mg
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A neurotoxic non-proteinogenic amino acid; cytotoxic to mouse primary cortical neurons at 3 mM; stimulates release of glutamate and induces oxidative stress in the same cells at 3 mM; enhances amyloid-β (25-35)-induced neuronal cell death in mouse primary cortical neurons at 0.1 mM; induces wet-dog shakes, rigidity, and clonic convulsions in rats at 500 UG/animal; induces parkinsonism in cynomolgus monkeys; has been found in commercial seafood
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Selleck Chemical LLC Pyr3 E4659-100MG
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Pyr3 is a selective and potent inhibitor of transient receptor potential canonical channel 3 (TRPC3) It inhibits TRPC3-mediated Ca2 influx in a dose-dependent manner with the IC50 value of 0 7 M It holds potential for treating TRPC3-related diseases like cardiac hypertrophy
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Selleck Chemical LLC Iberdomide S8760-1G
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Iberdomide (CC-220) is a novel oral immunomodulatory compound that targets cereblon part of the CRL4CRBN E3 ubiquitin ligase complex with an IC50 of 60 nM in a competitive TR-FRET assay Iberdomide (CC-220) induces apoptosis with antitumor and immunostimulatory activities
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Selleck Chemical LLC Sovleplenib E4580-5MG
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Sovleplenib(HMPL-523) is a highly potent and selective SYK inhibitor with IC50 of 0 025 M that exhibits anti-tumor activities in vitro and in vivo Sovleplenib exhibits synergistic activities in combination with BTK PI3K and Bcl2 family inhibitors in killing human-diffused large B cell lymphoma (DLBCL)
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Medchemexpress LLC GSK2606414 | 1337531-36-8 | 99.9% | 451.44 | 250 MG
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GSK2606414 is a cell-permeable and orally available protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) inhibitor with an IC50 of 0.4 nM. It inhibits PERK activation in cells and has been shown to inhibit the growth of a human tumor xenograft in mice.
- Cell-permeable
- Orally available
- Potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK)
- Inhibits PERK activation in cells
- Inhibits the growth of a human tumor xenograft in mice
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Cayman Chemical ANTIBODY OrotIdIn 10mg
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A pyrimidine nucleoside; urine levels are increased in rats following administration of allopurinol
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Cayman Chemical 1Stearoyl2PalmItoyl3Oleo 5mg
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A triacylglycerol that contains stearic acid at the sn-1 position, palmitic acid at the sn-2 position, and oleic acid at the sn-3 position; has been found in bovine milk
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Selleck Chemical LLC BAL-0028 E1970-5MG
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BAL-0028 (Compound 3) which belongs to the indazole class is an inhibitor of NLRP3 activation with an IC50 value of 25 nM BAL-0028 binds tightly to the NACHT domain of NLRP3 with KD values ranging from 104 to 123 nM BAL-0028 also exhibits anti-inflammatory activity
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Cayman Chemical Ala17-MCHtrIfluoroacetate 5mg
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An MCH-derived peptide and MCH receptor agonist; binds to MCH1 and MCH2 receptors in CHO cells expressing the human receptors (IC50s = 0.15 and 3.5 nM, respectively); induces calcium mobilization in HEK293 cells expressing the human receptors (EC50s = 17 and 54 nM, respectively)
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Apexbio Technology LLC (+)-SK&F 10047 hydrochloride 133005-41-1 10mg
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( )-SK F 10047 hydrochloride (CAS 133005-41-1) is a well-characterized 1 receptor agonist Studies demonstrate that it enhances hippocampal cholinergic activity in rodents increasing extracellular acetylcholine levels and exhibiting anti-amnesic effects in models of scopolamine-induced memory impairment These actions are reversed by 1 receptor antagonists indicating receptor-specific involvement Additionally in vivo data show that ( )-SK F 10047 mitigates conditioned fear stress when co-administered with anticonvulsants an effect modulated by dopaminergic pathways It is widely used to investigate 1 receptor function in the central nervous system Clinical data are not available
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Selleck Chemical LLC Sodium pyrophosphate 10H20 E4001-1G
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Sodium pyrophosphate decahydrate acts as a buffering agent a chelator and a hydrated salt nucleating agent Sodium pyrophosphate decahydrate can also be used to a raw material for synthetic laundry scent additives
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Selleck Chemical LLC Asandeutertinib E5912-100MG
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Asandeutertinib is an orally administered ATP-competitive irreversible deuterated third-generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR TKI) and a deuterium-stabilized derivative of osimertinib with the potential to treat advanced EGFR-mutated NSCLC
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Cayman Chemical 1 2DIoleoyl3Docosohexaenoy 5mg
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A triacylglycerol; has been detected in human breast milk
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